Introduction for CAIB
Pan cancers could be classified into Cluster 1: ICLowIL1BLow, Cluster 2: ICLowIL1BHigh, Cluster 3: ICMidCASP1High, Cluster 4: ICMidIL18High, Cluster 5: ICHighIL18Low, and Cluster 6: ICHighIL18High based on inflammasome signaling status. CAIB is a meta-server that could be used to identify inflammasome clusters using transcriptomic data (RNA-seq or microarray).
What can users do in CAIB
Profiling inflammasome signaling status of tumor samples based on RNA-seq or microarray profiles to choose reasonable therapeutic options; investigating the distribution of biological processes and pathways and immune status across inflammasome clusters.
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  • Example
Inflammasome-related gene sets
Inflammasome scores
Inflammasome clusters
Drug responses